The 7th Annual CBSD Center of Biomedical Research Excellence (CoBRE) Research Symposium was hosted at the Double Arrow Lodge in Seeley Lake, MT, Sept. 7-9, 2018. The annual research symposium provided us an opportunity to come together as a research community to discuss the latest research in our laboratories supported by CBSD. The symposium included lectures by Project Leaders who were supported by the CBSD NIH CoBRE grant and a selection of short talks by pilot project leaders and graduate students. We encouraged graduate and undergraduate students to participate in a poster session. There were also presentations from our Computational, X-ray and BioSpectroscopy Core Facilities so attendees could learn more about how these facilities could take their research projects in new directions.
Friday, Sept. 7, 2018
1:00 p.m. Check into hotel (the front desk is located in the Main Lodge), register, drop poster by room (if applicable), grab a snack and settle in
1:30 - 2:30 p.m. OPEN SESSION (Blackfoot Conference Center):CBSD Director Stephen R. Sprang, opening remarks and introduction.
CBSD Start Up Funded Investigator, , A bacteriophage enhances the virulence potential of Pseudomonas aeruginosa
2:30 - 3:30 p.m. OPEN SESSION (Blackfoot Conference Center): "Poster Preview" Talks
- Jill Farnsworth, Department of Biomedical & Pharmaceutical Sciences (BMED) Graduate Student, Negative allosteric modulation of NMDA receptors with GluN2A gain-of-function mutations
- Eric John, Department of Chemistry & Biochemistry Graduate Student, Hydrogen Bond Enhanced Halogen Bonding Helical Foldemers For Use as Synthetic Anion Channels
- Genevieve Krause, Department of Computer Science Graduate Student, Frameshift aware profile hidden Markov model for protein-DNA alignment
- Yan Li, Department of Chemistry & Biochemistry Graduate Student, Effective C-H bond cleavage by a high-valent di-cobalt(III ,IV) complex
- Alex Nord, Department of Computer Science Graduate Student, Splice-Aware Multiple Sequence Alignment of Protein Isoforms
- Jaspreet Kaur Osan, University of Alaska—Fairbanks Graduate Student, HLA-DM: An important factor in epitope editing tool
- Xiaobo Wang, Division of Biological Sciences Graduate Student, CCR4-NOT deadenylase complex contributes to FBF-1 function in germline stem cell maintenance in C. elegans
- Luke White, Division of Biological Sciences Graduate Student, Rift Valley fever virus affects host alternative splicing via mechanism involving splicing factor Tra2 β
3:30 - 4:00 p.m. Poster Session Participant set up if didn't occur earlier and break time.
4:00 - 6:00 p.m. OPEN SESSION: Poster Session & Refreshments.
6:15 p.m. Dinner (Pavilion)
~8:00 p.m. Campfire (fire restriction dependant)
9:30 p.m. Poster pick up deadline
Saturday, Sept. 8, 2018
7:00 - 9:00 a.m. Breakfast (Great Hall, Main Lodge)
8:30 - 10:45 a.m. OPEN SESSION (Blackfoot Conference Center): CBSD Core Facilities, 15 minute presentations with 10 minute Q&A (25 minutes total)
- , BCRL Director, “BioSpectroscopy Core-- Highlights from Year 7.”
- , MCCF Manager, “Molecular Computation Core Facility: CoBRE Year 7.”
- , MXDC Manager, “Macromolecular X-Ray Diffraction Core Facility Year 7 Update.”
- , Director, Small Molecule XRD, “Small Molecule Crystallography at 老虎机攻略”
- , Director, CBSD – “Mass Spec update: capabilities and future outlook”
10:45 - 11:00 a.m. Break with refreshments
11:00 a.m. -12:00 p.m. PRIVATE SESSION (Blackfoot Conference Center): Core Facility Round Table with EAC mentors
12:00 - 1:30 p.m. Open Lunch (Pavilion)
** 12:00 - 1:30 p.m. PRIVATE LUNCH (Hilltop Lodge)
- 老虎机攻略 Vice President for Research & Creative Scholarship Scott Whittenburg
- EAC: Suzanne Scarlata, Elizabeth Goldsmith and David Case
- IAC: Richard Bridges, Kasper Hansen, Bruce Bowler, Chris Palmer, Liz Putnam, J. Stephen Lodmell, Ekaterina Voronina, and Stephen Sprang
1:30 - 5:00 p.m. OPEN SESSION (Blackfoot Conference Center): Year 7 CoBRE Bridge Funded and Pilot Project Investigators, 20 minute presentations with 10 minute Q&A (30 minutes total)
- , The role of the AhR in the thymus
- , Induction of alternative splicing in Rift Valley fever virus infected cells
- , The System Xc- glutamate/cystine antiporter: differentiating substrates, inhibitors and allosteric regulators
- , Resolving receptor subunit composition using FRET-FLIM
- , Nanodisc Capillary Electrophoresis: Characterization of Chemical Interactions with Lipid Bilayers
- , Interplay between Silk Fibroin’s Structure and Its Adhesive Properties
- , Coordination of stem cell proliferation and differentiation through post-transcriptional control
5:00 - 6:00 p.m. Break
6:00 p.m. Keynote Dinner (Pavilion)
7:00 p.m. Keynote Speaker (Pavilion)
Keynote Speaker: , Associate Director of the Center for Biomolecular Structure and Dynamics (CBSD), 老虎机攻略
Title: Cytochrome c: On Being Flexible
Sunday, Sept. 9, 2018
7:00 - 9:00 a.m. Breakfast (Great Hall, Main Lodge)
8:00 - 10:00 a.m. OPEN SESSION (Blackfoot Conference Center): Current Junior Investigators, 30 minute presentations with 10 minute Q&A (40 minutes total)
- , Modulation of Epidermal Barrier Function by CYP26 inhibitors
- , On the Way of Designing Bio-inspired Dinuclear Catalysts for C-H bond Functionalization
- , Superior software systems for sussing out signals from sequences
10:00 a.m. OPEN SESSION (Blackfoot Conference Center): Closing remarks
10:15-11:15 a.m. PRIVATE SESSION (Blackfoot Conference Center): Current Junior Investigator and EAC Roundtable
- EAC: Suzanne Scarlata, Elizabeth Goldsmith and David Case
- Investigators: Dong Wang, Philippe Diaz and Travis Wheeler
11:15 - 1:00 p.m. PRIVATE SESSION (Hilltop Lodge): EAC Mentors final evaluation meeting and lunch
8:00 a.m. - 12:00 p.m. Check out (Main Lodge)